The original Andhra Pradesh Agricultural University was established on 12 June 1964 through the APAU Act 1963 with O. Pulla Reddy as the first vice-chancellor . It was formally inaugurated on 20 March 1965, by Lal Bahadur Shastri, the then Prime Minister of India in Hyderabad. On 23 June 1966, another milestone was the inauguration of the building program of the university by Indira Gandhi, the then Prime Minister of India. Later, it was renamed as Acharya N. G. Ranga Agricultural University on the 7th of November, 1996. Those institutions that were located in the residuary state of Andhra Pradesh were then grouped under a new university with the same name as Acharya N G Ranga Agricultural University was established in Guntur.[5][2][3]

Based on recommendation of the Committee and approval by the Competent Authority of ICAR (Indian Council of Agricultural Research), the ranking Status of Acharya N G Ranga Agricultural University for the year 2017-18 is 27 while the Acharya Jai Shankar Agricultural University is ranked at 12.

According to the Andhra Pradesh Agricultural University Act, 1963, Colleges of Agriculture and Veterinary Science, Hyderabad (affiliated to Osmania University), Agricultural College, Bapatla (affiliated with Andhra University), Sri Venkateswara Agricultural College and Andhra Veterinary College, Tirupati (affiliated to Sri Venkateswara University) were transferred to the new university in June 1964. About 41 agricultural research stations and four research stations were transferred to the university in July 1966 and May 1967, respectively.